Significance of Cannabis Testing

Cannabis Business Insights | Monday, May 22, 2023

The purpose of cannabis testing laboratories is to limit residual pesticides, processing chemicals, and microbial in cannabis products.

FREMONT, CA: Compliance and monitoring are essential to safeguarding the cannabis sector and discouraging customers from purchasing from the illicit market. As cannabis legalization progresses, demand for cannabis testing services has increased to verify that medical and recreational cannabis sold on the market satisfies quality and safety standards and is free of hazardous toxins. However, cannabis testing presents many obstacles, especially in the United States. Testing regulations vary between states and depend on the variety of cannabis from which the crop or product is derived.

Cannabis testing laboratories are in charge of quality control. Cannabis and cannabis-derived goods purchased from a licensed facility are subjected to a battery of tests that examine samples for a variety of constituents that affect product quality and safety. ISO/IEC 17025:2017, which refers to "General requirements for the competence of testing and calibration laboratories," is adhered to by the majority of cannabis testing laboratories. Some go further to comply with AOAC International and ASTM International requirements. All cannabis testing laboratories must be outfitted with sophisticated, sensitive analytical instruments and qualified technicians and analysts trained in each testing method.

Stay ahead of the industry with exclusive feature stories on the top companies, expert insights and the latest news delivered straight to your inbox. Subscribe today.

As the cannabis industry persists in evolving and cannabis laboratories utilize data to monitor lab performance, these data are becoming increasingly vital for—increasing consumer and healthcare provider confidence, risk management in a rapidly expanding market, and concentrating on quality products.

What is cannabis tested for?

Regulatory testing typically necessitates potency assessments to label the product appropriately. Pesticides, heavy metals, industrial chemicals, and microorganisms or microbial byproducts are also checked for in samples. This section will cover the various testing techniques available for this purpose.

Potency testing

Cannabinoid and terpenoid content are evaluated during potency testing to establish how much CBD and THC a product contains. GC with flame-ionization detection is a rapid method for assessing potency that permits accurate quantification of all the organic chemical species in a sample. Liquid chromatography is a more direct method for comprehensive cannabinoid profiling, as an analyst may additionally determine the amount of cannabinoid acid in a sample. The most prevalent techniques are high-performance liquid chromatography coupled with a diode array detector and liquid chromatography time-of-flight mass spectrometry. In contrast to a conventional UV-vis detector, HPLC-DAD simultaneously collects data over a spectrum of wavelengths.

Pesticide testing

Although the use of pesticides in agriculture is often regulated, cannabis remains banned in many nations and territories. In the United States, cannabis remains illegal at the federal level despite being authorized for recreational and medical use in many states. Hence, the Environmental Protection Agency (EPA) in the United States has not approved a list of pesticides for cannabis. The general protocol for pesticide testing involves an extraction step (to capture pesticides present in the sample), a clean-up step (to remove pigments or interferences that could affect the results), and an analysis step (typically liquid or gas chromatography with tandem mass spectrometry (LC/MS/MS or GC/MS/MS)). QuEChERS (rapid, simple, inexpensive, efficient, robust, and secure) is a well-known solid-phase extraction technique that removes pesticides. Certain chemicals are more receptive to GC analysis than LC; hence many laboratories employ both techniques to ensure that their workflow is sensitive to all the necessary substances.

Microbial testing

Cannabis is screened for yeast, mold, fungi, and typical bacteria such as E. coli and Salmonella. Culture-based detection is a simple method that has been the gold standard since the early 1900s; it requires particular nutrients and ambient conditions. The introduction of molecular diagnostic technologies eliminates the necessity for culture. For instance, quantitative polymerase chain reaction (qPCR) analysis is a high-tech method that allows analysts to collect and amplify all genomes present in a sample. Hence, the genetic barcode can be utilized to identify the microorganisms present in the sample.

Multiple obstacles make cannabis testing challenging. This section examines them in greater depth.

Regulations

Compliance testing mandated by the state for cannabis products has resulted in industry-wide public health protection. Yet, the absence of uniformity creates obstacles and opportunities for what needs to be monitored. In addition, makers of edibles and infused beverages confront their distinct obstacles. Most laboratories must balance regulatory compliance, customer needs, and scientific integrity, resulting in compromises.

Despite the lack of standardization, the sector is transitioning towards a quality-focused operation. For instance, over the past few years, the primary American body for testing standards has proposed and published new guidelines for cannabis testing, processing, cleaning, and transport. Similarly, cannabis companies are beginning to embrace the benefits of CGMPs, purpose-built laboratory informatics that supports regulatory compliance, and advanced data practices that preserve quality and meet the market's increasing complexity.

Capital expenses

A successful laboratory should aspire to have both highly skilled laboratory employees and high-tech, regulatory-compliant instruments. Establishing a cannabis testing lab costs between $2 million and $3 million, depending on the facility's financial capability and testing requirements. In addition, once operational, labs should purchase a high-quality system to prevent long-term risk. However, this can be costly to maintain due to the cost of people, audits, and proficiency exams. In addition, capacity is impacted by the number of quality control samples required for each batch and any re-runs necessitated by non-conformance.

More in News

In recent years, the cannabis industry has witnessed exponential growth, emerging from the shadows of prohibition to become a legitimate powerhouse in the global market. However, this rapid expansion also brings forth a unique set of challenges, particularly in establishing a resilient supply chain capable of withstanding fluctuations in demand, regulatory pressures, and operational risks. As the landscape continues to evolve, stakeholders must harness the power of technology, adhere to stringent compliance measures, and adopt innovative cultivation enhancements to build a robust supply chain. Leveraging Smart Packaging and Cultivation Innovation to Strengthen Cannabis Supply Chains In the cannabis industry, packaging has evolved into a vital instrument for both brand protection and regulatory compliance. Smart packaging technologies—such as QR codes and RFID tags—not only enhance transparency and product authenticity but also streamline adherence to complex regulatory requirements. QR codes enable consumers to access detailed information, including lab results, certificates of analysis, product specifications, dosage guidelines, and brand narratives, thereby fostering trust and empowering informed decision-making. Meanwhile, RFID technology enables real-time product tracking throughout the supply chain, ensuring compliance, optimizing logistics, and minimizing risks associated with loss or theft. Additionally, intelligent packaging plays a crucial role in maintaining product quality, potency, and shelf life, ultimately safeguarding the brand's integrity. Complementing these technological advancements, under-canopy lighting has emerged as a high-impact, low-effort innovation in indoor and vertical cannabis cultivation. By targeting the lower leaves and bud sites, this technique enhances light penetration, resulting in increased yields, improved plant health, and enhanced pest control. It also contributes to labor efficiency by reducing the need for manual defoliation. While successful implementation requires precise environmental management, under-canopy lighting offers a significant return on investment for growers seeking to boost productivity and quality with minimal disruption to existing operations. Strategic Risk Management as a Backbone for Long-Term Viability At the core of a practical risk management framework is regulatory compliance. This involves the continuous monitoring of state and federal regulations, the implementation of robust seed-to-sale tracking systems, recordkeeping, and strict adherence to packaging, labeling, and testing standards. Both internal and external audits play a critical role in identifying and closing compliance gaps before they escalate into serious issues. Diversification and contingency planning are equally essential. Overreliance on a single supplier or distribution channel exposes the supply chain to significant vulnerabilities. By diversifying suppliers, cultivators, and revenue streams, businesses can better withstand disruptions caused by factors such as crop failure, logistical challenges, or region-specific regulatory changes. Well-defined contingency plans for scenarios like product recalls, equipment failures, or natural disasters ensure operational continuity. Equally important is the integration of data-driven decision-making processes and the seamless flow of information. Deploying ERP systems that connect operations from cultivation through to compliance offers real-time visibility and supports accurate demand forecasting and resource planning. Clear communication channels and standardized operating procedures (SOPs) across all stakeholders—from growers to distributors and retailers—further enhance coordination and responsiveness. Cannabis businesses can move beyond simply reacting to challenges and instead build a proactive, adaptable, and ultimately resilient supply chain capable of navigating the industry for long-term success. The integration of technology, a steadfast commitment to compliance, and continuous innovation in cultivation are not merely options but necessities for thriving in this competitive and complex market. ...Read more
FREMONT CA:   The integration of artificial intelligence (AI) into cannabis cultivation and retail is transforming the industry by enabling smarter and more efficient operations. As legal cannabis markets continue to expand globally, producers and retailers face increasing pressure to optimize yields, enhance product quality, and improve overall efficiency. AI technologies, including machine learning and advanced data analytics, are being utilized to monitor environmental variables, automate cultivation workflows, and forecast consumer demand. This shift enhances resource management, reduces operational costs, and supports regulatory compliance in a growing and highly regulated industry. The Role of AI in Cannabis Cultivation Cannabis cultivation involves complex processes that necessitate precise control over various environmental factors. Monitoring conditions such as temperature, humidity, light, and nutrient levels requires meticulous attention. AI technology is increasingly used to streamline these tasks, saving growers time and enhancing accuracy. AI-powered systems continuously monitor and adjust environmental parameters in real-time, ensuring optimal growing conditions. Additionally, AI analyses plant health by processing data from various sensors, enabling the early detection of issues like disease or nutrient deficiencies. This proactive approach allows growers to respond quickly, minimising potential crop losses. Furthermore, AI-driven cameras are vital in monitoring plant growth and predicting yields with greater accuracy. By leveraging this data, growers can optimise their cultivation processes, increasing yields and conserving resources. Automated systems are also being integrated to manage labour-intensive tasks such as watering, feeding, and trimming, potentially reducing the reliance on manual labour. Predicting and Preventing Problems with AI: AI’s predictive capabilities represent one of its most valuable contributions to cannabis cultivation. By analysing sensor and camera data, AI can identify trends and foresee potential issues before they escalate. For instance, it can predict plant stress from temperature fluctuations or insufficient water supply. Early identification of these problems empowers growers to take preventive measures, safeguarding crop health and enhancing overall yields. This predictive functionality is a significant factor driving the growing popularity of AI in both cannabis cultivation and retail. Automating Pest and Disease Control: Pest and disease management poses significant challenges for cannabis growers. Traditional methods often depend on chemical treatments or manual inspections, which can be time-consuming and costly. AI technology provides a more efficient alternative. AI systems can detect early signs of pests or diseases by analysing plant images or sensor data. Upon detection, the systems can recommend or even implement treatments autonomously, thereby minimising the need for chemicals and reducing crop damage. Optimising Harvesting with AI: Harvesting cannabis is a labour-intensive process requiring precise timing to achieve the highest quality and potency. AI technology assists growers in determining the optimal harvest time by analysing data on plant maturity, trichome development, and environmental conditions. Additionally, automated harvesting systems powered by AI are becoming increasingly prevalent. These machines can execute harvesting tasks with precision, decreasing the likelihood of damage and boosting efficiency. Looking ahead, fully automated cannabis farms, where AI manages every aspect of cultivation, may become a reality. AI is reshaping cannabis cultivation and retail by enhancing customer experiences, streamlining operations, and increasing dispensary sales. By leveraging AI systems, retailers can offer personalised product recommendations based on customer data, improving satisfaction and engagement. AI-powered chatbots efficiently handle common inquiries, freeing staff to tackle more complex tasks. In inventory management, AI optimises processes by predicting demand and automating stock replenishment, which reduces waste and enhances profitability. Moreover, AI analyses consumer behaviour and social media trends, enabling retailers to make informed decisions about product offerings and marketing strategies. As cannabis e-commerce grows, AI will be crucial in optimising online shopping experiences through personalised recommendations and improved website navigation. The Future of AI in Cannabis Cultivation and Retail The integration of AI in cannabis cultivation and retail is still evolving, yet its potential remains vast. More sophisticated AI systems are expected to emerge as technology advances, helping cannabis businesses enhance efficiency, reduce costs, and provide superior customer experiences. In the future, fully automated cannabis farms may become commonplace, with AI overseeing all cultivation aspects. AI-powered dispensaries could incorporate virtual assistants to guide customers in finding ideal products, while predictive analytics will enable retailers to anticipate consumer trends. As growers leverage AI technologies to monitor environmental conditions, predict trends, and automate labour-intensive tasks, they can achieve higher yields and better-quality products while minimising risks and costs. Similarly, retailers benefit from personalised recommendations and streamlined inventory management, increasing customer satisfaction and engagement. With ongoing advancements in AI, the cannabis sector is set to become more innovative and competitive. Embracing these technologies will foster sustainability and profitability and position businesses at the forefront of an evolving market landscape. ...Read more
The cannabis industry is on the brink of a technological revolution. Innovations in cannabis technology transform cultivation efficiency, purify products, and enhance sustainability within the sector. Precision Agriculture Precision agriculture is perhaps the most significant trend in cannabis technology. More accurate environmental conditions, in terms of humidity, temperature, and nutrient levels, are determined using real-time data from smart sensors. This ensures that optimum growth conditions are maintained, which results in higher yields and better-quality cannabis. Precision agriculture increases efficiency while at the same time fostering sustainability by avoiding the waste of all resources. AI-Driven Production In the cannabis sector, artificial intelligence (AI) is causing a stir. AI-powered systems may analyze large volumes of data to maximize every facet of cannabis production. From predicting the best harvest times to automating quality control, AI is set to revolutionize how cannabis is grown and processed. This technology allows for more consistent and high-quality products, meeting the growing demand for premium cannabis. Advanced Extraction Methods The second interesting development is in the evolution of cannabis extraction technology. There is an upsurge in new, solvent-free extraction methods. Solvent-free extraction methods enable pure and powerful cannabis products without the hassle of chemicals. More advanced efficiency-gaining machines also enhance efficiency in producing cleaner, rarer, refined products. This is driven by consumer demand for quality and safe products. Sustainability Practice The cannabis industry will need to focus more on sustainability in the future. Cultivation technology innovations, including LED lighting and renewable energy solutions, are reducing the environmental impact of cannabis farming. These practices lower energy consumption while making the industry more sustainable. With increasing environmental consciousness among consumers, adopting sustainable practices will be crucial for the industry's growth. Personalized Cannabis Products The trend for personalized cannabis products is on the rise. Through AI, companies can create custom products tailored to individual needs. Whether it's a specific THC/CBD ratio or particular terpenes for desired effects, personalized cannabis products are becoming more accessible. This customization enhances the consumer experience by offering products tailored to specific preferences and health requirements. Changes in Marketing and Branding With the maturity of the cannabis market, marketing and branding strategies have evolved. The onus of education and responsible consumption is now upon the brands. Businesses are now leaving behind the flashy, unregulated ads and shifting to informative campaigns. In this respect, advanced compliance software also supports the changing landscape, aiding businesses in complying with regulations that are now in place. Additionally, the brands emphasize educating the consumer on the advantages and responsible use of cannabis. ...Read more
The legal cannabis, CBD, and hemp sectors are sweeping the nation, and numerous potential legislation to legalize cannabis at the federal level are now being debated. Given that the majority of Americans support medical cannabis in a society split by practically every other issue imaginable — it's not surprising that cannabis is rapidly approaching full legalization. Cannabis is poised to become legal for adults in Minnesota. Many states begin slowly, but as the effects of additional jobs and tax dollars for cities and counties rise, as does demand, people will see pressure to speed things ahead more quickly. With federal cannabis legalization in uncertainty and individual states authorizing cannabis sales and production, professionals such as CPAs find themselves in a difficult position. On the one side, cannabis businesses require accounting support to remain compliant and maintain their licenses.The truth is that thousands of businesses are springing up all over the place, and there aren't enough qualified accountants to go around. The primary misconceptions around offering accounting services to the cannabis and CBD/hemp sectors are listed below: This is the "all-cash" industry. Actually, credit unions and banks serve cannabis businesses in various states. Businesses generate a large amount of cash. Thus, cash controls and processes are crucial for preventing fraud and theft. Furthermore, many cannabis business owners possess two to ten non-cannabis firms, such as a real estate or equipment company, which have better access to finance. The federal government is now reviewing the SAFE Banking Act, and cannabis businesses should soon have simpler access to banking and merchant services. Cannabis must be a terrible "niche" for CPAs: There are currently very few CPAs in the niche, so there is a huge opportunity. Many surveys have shown that solo CPAs suffer the most when obtaining exceptional clients, and if that's the case for specific companies, this could be their opportunity to discover high-paying clients effortlessly. Many people will spend in the six figures for world-class accounting, tax, and CFO services. When one considers that a modest mom-and-pop cannabis firm, whether a farm, dispensary, or vertical integration, can soon grow to a $10-$20 million company, these clients are willing to pay high prices for reliable accounting and tax services. Cost accounting is complex, and the founders and investors value accuracy. ...Read more